What is the best treatment approach for a 25-year-old woman at 33 weeks gestation with leakage of clear fluid?

The best treatment approach for a 25-year-old woman at 33 weeks gestation with leakage of clear fluid is to administer antibiotics and corticosteroids while admitting her for expectant management.

In this scenario, the leakage of clear fluid suggests a possible premature rupture of membranes (PROM). The goal in cases of PROM, especially with preterm gestation, is to manage the pregnancy conservatively if the mother and fetus are stable. Expectant management allows the fetus more time to develop while monitoring for any signs of infection or labor progression.

Administering antibiotics helps reduce the risk of developing an infection, which is a significant concern with PROM. Corticosteroids are indicated to accelerate fetal lung maturity, an essential factor in cases of preterm birth.

This approach differs from induction of labor, which would not be the preferred course of action unless there's a clear indication of maternal or fetal distress, as premature delivery can bring significant neonatal risks. The strategy of monitoring the patient in a hospital setting allows healthcare providers to act quickly if the situation changes while still maximizing fetal health.